Skeletal Muscle Differentiation Kit
Differentiate human pluripotent stem cells to skeletal muscle
The world’s first protocol to differentiate human pluripotent stem cells to skeletal muscle with high yields and without cell sorting or genetic manipulation. Myotubes are contractile, express typical muscle markers and show striated sarcomeres. The process yields almost pure populations of myogenic cells; it is highly efficient and works robustly with all pluripotent stem cell lines – critical prerequisites for effective cell-based disease modeling and drug development.
Generation of Muscle Cells in 3 Steps
Muscle is generated from human pluripotent stem cells in 3 steps, via satellite-like progenitor cells and myoblasts that then fuse to multinucleated myotubes in the third step. This third generation of the process includes an optional enhanced fusion formulation, depending on your desired phenotype.