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 A comprehensive range of monoclonal, polyclonal and secondary antibodies
 A comprehensive range of monoclonal, polyclonal and secondary antibodies
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High quality human and animal biospecimensÂ
High quality human and animal biospecimensÂ
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Primary cells and cell lines, 3D cell culture products and transfection reagents
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For the study of apoptosis, DNA damage, oxidative stress, angiogenesis, enzyme activity an...
For the study of apoptosis, DNA damage, oxidative stress, angiogenesis, enzyme activity an...
Featured Research
Gut bacteria Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice
- Dr. Mahesh S. Desai and colleagues from the Department of Infection and Immunity at Luxembourg Institute of Health published a paper revealing that depriving mice of dietary fiber alters the gut microbiome, leading to exacerbated allergic reaction to food allergens.Â
- The alteration in the gut microbiome caused an increase in the mucin-degrading bacterium Akkermansia muciniphila. This was found to be associated with intestinal barrier dysfunction, increased expression of type 1 and 2 cytokines, and IgE-coated commensals in the colon, resulting in an exacerbated allergic reaction to food allergens.Â
- The researchers used mouse anti-ovalbumin IgE monoclonal antibody and mouse anti-ovalbumin IgG1 monoclonal antibody from AMSBIO to conduct allergen-specific ELISA assays. This technique enabled them to quantify the levels of allergen-specific IgE and IgG1 antibodies present in serum samples.Â

Citations
Akkermansia muciniphila exacerbates food allergy in fibre-deprived miceÂ
Parrish, A. et al., (2023). Nature Microbiology, 8(10), 1863–1879. Â