iMatrix-511 Recombinant Laminin E8 Fragments

Highly Efficient ES/iPS Cell Culture

iMatrix-511 is an innovative cell culture matrix compatible with a wide variety of cell types, and exceptionally well suited for pluripotent stem cells. This product is comprised of recombinant Laminin-511 E8 protein fragments which permit ES/iPS cells to be maintained in feeder-free culture conditions, enables the passaging of single cells, and provides greater adhesion than full-length Laminin, Vitronectin or Matrigel.

  • Ideal for feeder-free cell culture
  • Provides superior adhesion of human ES and iPS cells
  • Enables the passaging of single cells
  • Compatible across a wide variety of cell types
  • Makes it easy to achieve extended cultures of hES/hiPS cells
  • Enables efficient bulk production

Culture More ES & iPS Cells

Figure 1 results show that the number of cells multiplied by 200 or more with the use of Laminin-511 E8 fragment in comparison with the conventional method (colony method).

Superior Binding Activity

The Binding activity of Laminin 511 E8 Fragment against ES cell was better than Full length 511 and traditional substrate. The same function was confirmed in human iPS cells.

iMatrix-511 Silk

iMatrix-511 Silk is human recombinant Laminin-511 E8 with the same functions and performance as those of iMatrix-511, the only difference being is that it is expressed in transgenic silkworm cocoon rather than CHO-S cells. The highly productive transgenic silkworms make recombinant laminin fragment at a competitive price.