CRISPR Gene Editing

Cutting edge services for your genome editing research

CRISPR/Cas9 is the latest tool in genome editing. A simple yet powerful technology, CRISPR/Cas9 has been adapted from a natural defense mechanism of bacteria and archaea, and can be utilized to target specific sites in the genome. This revolutionary technology allows for the manipulation of specific genes with high specificity and low cell toxicity. AMSBIO offers a range of custom services to meet the exact requirements of your gene editing projects. The fast turnaround and affordability of our CRISPR/Cas9 services helps to accelerate your genome editing research.

Our Services

Guide RNA

Specific and potent guide RNA (gRNA) is crucial for successful genome editing. Our custom gRNA cloning service is a cost-effective and fast tool to accelerate your research. We offer target sequence cloning into any of our CRISPR/Cas9 vectors with the following two options:

  • Self-design: You provide the target sequences, choose a vector and we will construct the plasmid
  • Our design: You provide around 100bp genome sequence and we will design the target sequences for you using our proprietary gRNA design tool

Donor Vectors

We also offer the following services for the construction of custom donor vectors for genome editing:

  • Target sequence cloning into CRISPR/Cas vector
  • Donor vector construction with a predesigned cassette
  • Donor vector of your own design

Custom CRISPR Kits

We offer a service to design and produce custom knock-out, knock-in or point mutation CRISPR kits, which provides you with everything you need for your specific genome editing research in one simple kit.

Included in the CRISPR Kit:

      • crRNA custom-designed for your project
      • tracrRNA
      • Cas9 nuclease protein
      • Donor construct custom-designed for your project (may be provided as oligonucleotide or plasmid, depending on your project needs)

CRISPR Cell Line Modification Service

We offer a comprehensive cell line engineering service based on the CRISPR-Cas9 system. We can perform projects such as gene knockouts, targeted integrations, point mutations, and more in your favorite cell line.

Schematic Representation

CRISPR Gene Editing Request Form

Let's get started

Complete our service request form and we will contact you to discuss your requirements.