Hyaluronan (also known as Hyaluronic Acid, or HA) is a glycosaminoglycan with a simple conserved structure. It is widespread in the extracellular matrix, playing many roles in health and disease. Because of its simplicity and ubiquity, Hyaluronan is not immunogenic so classical immunological analysis has not been possible. Available in biotinylated and purified formats – AMSBIO HABP is produced as a recombinant protein in E. coli transfected with human versican G1-domain. Recombinant production of AMSBIO HABP means that it offers higher safety compared with animal-derived HABP. AMSBIO recombinant HABP specifically detects Hyaluronan, binding to Hyaluronan from all species and tissues. It does not cross-react to other Glycosaminoglycans or to DNA.
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