TET2 Chemiluminescent Assay Kit

Name: TET2 Chemiluminescent Assay Kit
Brand: AMS.50652
SKU: AMS.50652
Availability: InStock

Product Code

AMS.50652

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Overview

The TET2 Chemiluminescent Assay Kit is designed to measure TET2 activity for screening and profiling applications. TET2 belongs to the Ten Eleven Translocation (TET) family proteins that catalyze 5-methylcytosine oxidation and generate 5-methylcytosine derivatives|including 5-hydroxymethylcytosine. TET2 is one of the most frequently mutated genes in myeloid malignancies. The key to the TET2 Chemiluminescent Assay Kit is a highly specific antibody that recognizes hydroxymethylated substrate. With this kit|only three simple steps on a microtiter plate are required for detection of TET2 activity. First|TET2 enzyme is incubated with the methylated substrate for two hours. Then the primary antibody is added. Next|the plate is treated with an HRP-labeled secondary antibody. Finally|the HRP substrate is added to produce chemiluminescence that can be measured using a chemiluminescence reader.

Product Specifications

More Information
SKU	AMS.50652
Size	96 reactions
Application	Great for studying enzyme kinetics and HTS applications.
Gene synonyms	Ten-eleven translocation 2 protein, methylcytosine dioxygenase TET2
Storage	Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS
Research Areas	Epigenetics

For more details visit our Histone Methylation page >

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TET2 Chemiluminescent Assay Kit

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