Spike Trimer (S1+S2) (K417T|E484K|N501Y)|His-Tag (SARS-CoV-2) Recombinant
Product Code
AMS.100988-2
$0.00
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Recombinant SARS-CoV-2 Spike protein in its homotrimeric form|containing S1+S2 subunits and encompassing amino acids 16-1213. This protein contains three mutations: K417T|E484K and N501Y that have been found in emerging SARS-CoV-2 Variants of Concern and may lead to higher transmissibility and infectivity. This mutant Spike Trimer will be useful for structure-function studies|testing of neutralizing antibodies|or antibody and drug screening.  The construct also contains a C-terminal His-tag. Note that the expected MW of the S1+S2 monomer is 136kDa but migrates at a higher MW in SDS-PAGE due to glycosylation. The recombinant protein is ?90% pure following affinity purification.
| SKU | AMS.100988-2 |
|---|---|
| Size | 1 mg |
| Species | SARS-CoV-2 |
| Expression Host | HEK293 |
| Tag | His |
| Tag position | C-terminal |
| Accession No | MN908947 |
| Gene id | MN908947 |
| Gene synonyms | coronavirus, covid, covid-19, covid19, Sars-cov-2 p1, sars cov 2 Spike, sarscov2, SARS-CoV-2 variant b11281, SARS-CoV-2 variant b1135, K417T mutation, Brazil coronavirus, SARS-CoV-2 Brazil, B1135 variant, South Africa variant, 100988-1, 100988-2 |
| Format | Aqueous buffer solution. |
| Storage | At least 6 months at -80C. |
| Shipping Temp | -80C (dry ice) |
| Supplier Name | BPS |