Spike (BA.4/5/ Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

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78644-1
$0.00
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The Spike protein of BA.4 and BA.5 variants of SARS-CoV-2 have identical mutations. In this datasheet/ the spike protein of BA.4 and BA.5 are referred to as BA.4/5.The Spike (BA.4/5/ Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BA.4/5 mutations; see below for details) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene/ therefore/ the spike-mediated cell entry can be measured via luciferase activity. The Spike (BA.4/5 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 BA.4/5 variant in a Biosafety Level 2 facility.The Spike (BA.4/5 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 ( #79951). Spike VSV Delta G is preferred for use in cells such as Vero-E6 and Calu-3.Spike Mutations in BA.4/5/ Omicron Variant:Del69-70/ T19I/ LPPA24-27S/ G142D/ V213G/ G339D/ S371F/ S373P/ S375F/ T376A/ D405N/ R408S/ K417N/ N440K/ L452R/ S477N/ T478K/ E484A/ F486V/ Q498R/ N501Y/ Y505H/ D614G/ H655Y/ N679K/ P681H/ N764K/ D796Y/ Q954H/ N969K
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SKU 78644-1
Size 100 ul
Species SARS-CoV-2
Application Screen or titrate neutralizing antibodies against SARS-CoV-2 Spike proteinModel virus entry in Vero-E6/ Calu-3/ and ACE2-HEK293 cells
Storage The VSV Delta G pseudovirus is shipped with dry ice. For long-term storage/ it is recommended to store the virus at -80C. 
Shipping Temp -80C (dry ice)
Supplier Name BPS
For more details visit our Vesicular stomatitis virus (VSV) tools page >