Spike (BA.2.12.1/ Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

Name: Spike (BA.2.12.1/ Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)
Brand: 78643-2
SKU: 78643-2
Availability: InStock

Product Code

78643-2

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Overview

The Spike (BA.2.12.1/ Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BA.2.12.1 mutations; see below for details) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene/ therefore/ the spike-mediated cell entry can be measured via luciferase activity. The Spike (BA.2.12.1 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 BA.2.12.1 variant in a Biosafety Level 2 facility.The Spike (BA.2.12.1 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 ( #79951). Spike VSV Delta G is preferred for use in cells such as Vero-E6 and Calu-3.Spike Mutations in BA.2.12.1/ Omicron Variant:T19I/ LPPA24-27S/ G142D/ V213G/ G339D/ S371F/ S373P/ S375F/ T376A/ D405N/ R408S/ K417N/ N440K/ L452Q/ S477N/ T478K/ E484A/ Q493R/ Q498R/ N501Y/ Y505H/ D614G/ H655Y/ N679K/ P681H/ S704L/ N764K/ D796Y/ Q954H/ N969K

Product Specifications

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SKU	78643-2
Size	500 ul x 2
Species	SARS-CoV-2
Application	Screen or titrate neutralizing antibodies against SARS-CoV-2 Spike proteinModel virus entry in Vero-E6/ Calu-3/ and ACE2-HEK293 cells
Storage	The VSV Delta G pseudovirus is shipped with dry ice. For long-term storage/ it is recommended to store the virus at -80C.Â
Shipping Temp	-80C (dry ice)
Supplier Name	BPS

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Spike (BA.2.12.1/ Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

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