SARS-CoV-2 Spike Trimer (N501Y, D614G), His Tag (MALS verified)
Product Code
AMS.SPN-C52Hp-500ug
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SARS-CoV-2 S protein (N501Y,D614G), His Tag (SPN-C52Hp) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (N501Y, D614G)). The N501Y/D614G mutations were identified in multiple SARS-CoV-2 variants which emerged in the United Kingdom (known as B.1.1.7, 20B/501Y.V1 or VOC 202012/01), South Africa(known as B.1.351 or 20C/501Y.V2), and Brazil (Known as P.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
SKU | AMS.SPN-C52Hp-500ug |
---|---|
Size | 500 ug |
Species | Virus, SARS-CoV-2 |
Expression Host | HEK293 |
Gene symbol | Spike protein |
Tag | His |
Accession No | QHD43416.1 (N501Y, D614G) |
Gene synonyms | Spike,S protein,Spike glycoprotein,S glycoprotein |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |