Anti-PSMA-Anti-CD3 IgG format Bispecific Antibody

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AMS.101242-2
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Anti-PSMA-Anti-CD3 IgG format bispecific antibody is a purified recombinant human bispecific antibody with T cell Engager. This bispecific antibody has been tested for specific activity in the functional reporter assay using NFAT-luc reporter Jurkat cell line ( #60621) in the presence of PSMA-CHO cells ( #79641-H). PSMA (Prostate-Specific Membrane antigen)|also known as FLOH1 (folate hydrolase 1) and NAALADase I (N-acetyl-L-aspartyl-L-glutamate peptidase I) is a transmembrane protein highly expressed in the intestine|the prostate|and the nervous system. The protein is a glutamate carboxypeptidase involved in folate metabolism and may be involved in pathological conditions such as hyperhomocysteinemia (intestine) and glutamate toxicity (nervous system). PSMA is overexpressed in prostate cancer cells and is the target of an increasing number of diagnostic and therapeutic approaches used for the treatment of prostate cancer.
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SKU AMS.101242-2
Size 100 ug
Species Human
isotype IgG, IgG1
Format Aqueous buffer solution
Storage At least 12 months at -80C.
Shipping Temp -80C (dry ice)
Supplier Name BPS
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