PDE1B-HEK293 Recombinant Cell line

Name: PDE1B-HEK293 Recombinant Cell line
Brand: AMS.60402
SKU: AMS.60402
Availability: InStock

Product Code

AMS.60402

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Overview

Recombinant HEK293 cell line expressing human PDE1B (phosphodiesterase 1B/ accession number NM_000924). N-terminal His-tagged human PDE1B has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The function of PDE1B was characterized by a cell-based cGMP assay. In this assay system/ cells co-express atrial natriuretic peptide (ANP) receptor A (a guanylate cyclase)/ cyclic nucleotide5gated cation channel CNGA2/ and the photoprotein aequorin. Intracellular cGMP level is monitored via aequorin luminescence induced by Ca²⁺ influx through CNGA2/ acting as the intracellular cGMP sensor.

Product Specifications

More Information
SKU	AMS.60402
Size	2 vials
Species	Human
Cell Line	HEK293
Tissue Type	Kidney
Application	Useful to monitor cAMP and PDE1B signaling pathway activity and to screen activators or inhibitors of PDE1B.
Accession No	NM_000924
Gene id	NM_000924
Gene synonyms	PDE1B, phosphodiesterase 1B
Storage	Store in liquid nitrogen immediately upon receipt.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS

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PDE1B-HEK293 Recombinant Cell line

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