Human CD28H / IGPR-1 Protein, Fc Tag (MALS verified)
Product Code
AMS.CDH-H5251-100ug
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CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
SKU | AMS.CDH-H5251-100ug |
---|---|
Size | 100 ug |
Species | Human |
Expression Host | HEK293 |
Gene symbol | CD28H |
aa sequence | Leu 23 - Gly 150 |
Tag | FC |
Label/Conjugate | Unconjugated |
Accession No | AAH15655.1 |
Gene description | Human |
Gene synonyms | TMIGD2,IGPR1 |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |