GITR / NF-kappaB Luciferase Reporter - Jurkat Cell Line

Name: GITR / NF-kappaB Luciferase Reporter - Jurkat Cell Line
Brand: AMS.60546
SKU: AMS.60546
Availability: InStock

Product Code

AMS.60546

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Overview

This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene; TNFRSF18; CD357) and an NF-kappaB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by stimulants/ endogenous NF-kappaB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. The cells have been validated using purified human GITRL and anti-GITR neutralizing antibody.

Product Specifications

More Information
SKU	AMS.60546
Size	2 vials
Species	Human
Cell Line	JURKAT
Tissue Type	Lymphoid Tissue
Application	This cell line is suitable for monitoring the activity of NF-kB signaling in response to GITR ligand (GITRL).
Storage	Store in liquid nitrogen immediately upon receipt.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS
Research Areas	Immunology

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The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

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GITR / NF-kappaB Luciferase Reporter - Jurkat Cell Line

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