CSF1R / SRE - Reporter HEK293 Recombinant Cell Line

Product Code
AMS.79380
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The CSF1R SRE HEK293 recombinant cell line has been transfected with full-length human CSF1R cDNA (NP_005202) under a CMV promoter for high constitutive expression. The SRE-luciferase reporter is also stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of the Serum Response Element upstream of a minimal promoter. Upon ligand binding/ active CSF1R will initiate the MAPK/ERK signaling pathway/ leading to expression of the SRE-controlled luciferase reporter.
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SKU AMS.79380
Size 2 vials
Species Human
Cell Line HEK293
Tissue Type Kidney
Application Monitor the CSF1R/MAPK/ERK signaling pathway activity and SRF-mediated activity. Screen for activators or inhibitors of the CSF1R/MAPK/ERK signaling pathway.
Gene synonyms CSF1R, CSFR, CD115, M-CSF-R
Storage Store in liquid nitrogen immediately upon receipt. Do not store for long-term at -80C or on dry ice.
Shipping Temp -80C (dry ice)
Supplier Name BPS
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