CD40/NF-kappaB Luciferase Reporter HEK293 Cell Line
Product Code
AMS.60626
$0.00
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Recombinant HEK293 cell line expressing full length human CD40 (Tumor necrosis factor receptor superfamily member 5; TNFRSF5). Expression is confirmed by flow cytometry and Western Blot. This NF-kappaB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by human CD40 ligand/ NF-kappaB transcription factor binds to the DNA response elements to induce transcription of the luciferase gene.
SKU | AMS.60626 |
---|---|
Size | 2 vials |
Species | Human |
Cell Line | HEK293 |
Tissue Type | Kidney |
Application | The CD40 NF-kappaB Reporter HEK293 Stable Cell Line is ideal for High Throughput Screening (HTS) to identify potential CD40 agonistic monoclonal antibodies and CD40-specific inhibitors. |
Gene synonyms | CD40 cell line, luciferase reporter, CD40 NF-kB cell line, NFkB cell line |
Storage | Immediately upon receipt/ store vials in liquid nitrogen. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |
Research Areas | Immunology |