BACE1 Assay Kit

Product Code
71656
$0.00
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Bace1 (beta-secretase 1) is an aspartic protease that is involved in the processing of the Amyloid precursor protein (APP). Cleavage of APP by BACE1 followed by gamma-secretase results in beta-amyloid peptide production|which ultimately leads toxic Abeta accumulation. In Alzheimer's disease (AD)|it has been widely accepted that Abeta aggregation plays a critical role in AD pathogenesis|suggesting that BACE1 could be a potential target to treat AD. The BACE1 FRET Assay Kit is designed to measure BACE1 activity for screening and profiling applications based on fluorescence resonance energy transfer (FRET) using a labeled peptide substrate (below).
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SKU 71656
Size 96 reactions
Alternate SKU AMS.71656
Application Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Gene synonyms beta-site amyloid precursor protein cleaving enzyme 1, ASP2
Storage At least 12 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Shipping Temp -80C (dry ice)
Supplier Name BPS
Research Areas Neuroscience