BACE1 Assay Kit
Product Code
71656
$0.00
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Bace1 (beta-secretase 1) is an aspartic protease that is involved in the processing of the Amyloid precursor protein (APP). Cleavage of APP by BACE1 followed by gamma-secretase results in beta-amyloid peptide production|which ultimately leads toxic Abeta accumulation. In Alzheimer's disease (AD)|it has been widely accepted that Abeta aggregation plays a critical role in AD pathogenesis|suggesting that BACE1 could be a potential target to treat AD. The BACE1 FRET Assay Kit is designed to measure BACE1 activity for screening and profiling applications based on fluorescence resonance energy transfer (FRET) using a labeled peptide substrate (below).
SKU | 71656 |
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Size | 96 reactions |
Alternate SKU | AMS.71656 |
Application | Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
Gene synonyms | beta-site amyloid precursor protein cleaving enzyme 1, ASP2 |
Storage | At least 12 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |
Research Areas | Neuroscience |