amsbio - page banner
Product Search:
Google Site Search>>
Change my country > : UNITED STATES
Home
Promotions
Custom Services
Presentations
Events
Partners
View Basket
Contact Us
Customer service team direct on (UK) +44(0)1235 828 200 : (CH) +41(0)91-604 55 22 : (DE) +49(0)69-77 90 99

PARP / PARG Kits and Reagents

amsbio.com - PARP / PARG Kits and Reagents
amsbio supplies a unique ranage of Poly-ADP-ribose polymerase (PARP) assay kits, enzymes & antibodies for DNA damage research.

Search our online catalogue or download our PARP presentation for more information.

Poly-ADP-ribose polymerase catalyzes the NAD dependent addition of poly-ADP-ribose (PAR) to adjacent nuclear proteins. PARP plays an important role in DNA repair but can also lead to apoptosis by depleting the cellular NAD pool. PARP inhibition has been shown to prevent tissue damage in animal models of myocardial & neuronal ischemia, diabetes, septic shock, & vascular stroke.

PARP Enzyme:
  • Standard PARP purified to ~50% purity (useful as positive control for Western blot analysis of ribosylated proteins & PARP Activity Assays.)
  • High specific activity (HSA) PARP enzyme purified to >95% (for detailed studies & drug discovery applications).
PARP Catalytic Domains Recombinant proteins from E. coli containing plasmids harboring the PARP-CAT gene.

PARP and PAR Antibodies PARP monoclonal antibody can be used for analysis of PARP protein levels & cleavage of PARP in apoptotic cells. PAR antibody: specific for PAR polymers synthesized by a variety of PARP isoforms (PARP-1,-2,-3, tankyrase, vPARP, and others).

PARP & PARG Kits PARP Assay Kits measure incorporation of biotinylated Poly(ADPribose) onto histone proteins, allowing screening of PARP inhibitors & measurement of PARP activity in cell and tissue extracts. PARG Assay Kits allow screening of PARG inhibitors & measurement of PARG activity in cell extracts. Learn more, click here: Assay PARP and PARG Kits.
Product News:
Latest Product News:
New enzymes and assay kits New enzymes and assay kits
BL21 Gen-X Competent E. coli BL21 Gen-X Competent E. coli
Cellufine Cellulose Chromatography Media Cellufine Cellulose Chromatography Media
Cultrex Cell Migration/Invasion Kits Cultrex Cell Migration/Invasion Kits
Custom Phospho-Specific Polyclonal Antibody Service Custom Phospho-Specific Polyclonal Antibody Service
Directed in vivo Angiogenesis Assay DIVAA Directed in vivo Angiogenesis Assay DIVAA
Dr. P - DNA, RNA, and protein sets Dr. P - DNA, RNA, and protein sets
ExpressArt mRNA Amplification Kits and Reagents ExpressArt mRNA Amplification Kits and Reagents
FACSmax Cell Dissociation Solution FACSmax Cell Dissociation Solution
GenePORTER 3000 Transfection Reagent GenePORTER 3000 Transfection Reagent
HAMA Blocker: Human Anti-Mouse Antibody (HAMA) interference HAMA Blocker: Human Anti-Mouse Antibody (HAMA) interference
Human Endothelial Progenitor Cells Human Endothelial Progenitor Cells
Iso-Gold Rapid Mouse-Isotyping Kits Iso-Gold Rapid Mouse-Isotyping Kits
MycoGONE Mycoplasma Antibiotics Cocktail MycoGONE Mycoplasma Antibiotics Cocktail
NeuroPure Primary Rat Neuronal Cells NeuroPure Primary Rat Neuronal Cells
New enzymes and assay kits New enzymes and assay kits
New SERVA BluePrep Kits New SERVA BluePrep Kits
Oris Cell Migration & Invasion Assays Oris Cell Migration & Invasion Assays
Oris Pro Cell Migration Assays Oris Pro Cell Migration Assays
Oxidative stress assay kits, antibodies, enzymes and reagents Oxidative stress assay kits, antibodies, enzymes and reagents
PARP / PARG kits & reagents PARP / PARG kits & reagents
PathClear pathogen-free Cultrex BME PathClear pathogen-free Cultrex BME
RNA isolation from FFPE & LCM RNA isolation from FFPE & LCM
Select-HA: Hyaluronic Acid LoLadders Select-HA: Hyaluronic Acid LoLadders
SoluLyse Bacterial Protein Extraction Reagent SoluLyse Bacterial Protein Extraction Reagent