Rhesus macaque VEGF R1 / Flt-1 Protein, Mouse IgG2a Fc Tag, low endotoxin

Product Code
AMS.VE1-R5257-100ug
$485.00
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Vascular endothelial growth factor receptor 1 (VEGFR1) is also known as Fms-like tyrosine kinase 1 (FLT-1)|Tyrosine-protein kinase receptor FLT|is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily|Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR1 is detected in normal lung|but also in placenta|liver|kidney|heart and brain tissues and specifically expressed in most of the vascular endothelial cells|and also expressed in peripheral blood monocytes. VEGFR1 acts as a cell-surface receptor for VEGFA|VEGFB and PGF|and plays an essential role in the development of embryonic vasculature|the regulation of angiogenesis|cell survival|cell migration|macrophage function|chemotaxis|and cancer cell invasion. VEGFR1 may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. VEGFR1 can promote endothelial cell proliferation|survival and angiogenesis in adulthood.
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SKU AMS.VE1-R5257-100ug
Size 100 ug
Species Monkey, Rhesus
Expression Host HEK293
Gene symbol VEGF R1
aa sequence Ser 27 - Asn 756
Tag FC
Label/Conjugate Unconjugated
Accession No XP_001117928.2
Gene synonyms FLT,VEGFR1,FLT1
Format Powder
Storage -20C
Shipping Temp RT
Supplier Name ACROBiosystems Inc.