Human PD-L2 / B7-DC Protein, Fc Tag (HPLC verified)
Product Code
AMS.PD2-H5251-100ug
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Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
SKU | AMS.PD2-H5251-100ug |
---|---|
Size | 100 ug |
Species | Human |
Expression Host | HEK293 |
Gene symbol | PD-L2 |
aa sequence | Leu 20 - Pro 219 |
Tag | FC |
Label/Conjugate | Unconjugated |
Accession No | AAI13679 |
Gene synonyms | PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2 |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |