Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag

Name: Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag
Brand: AMS.NR1-H5252-1mg
SKU: AMS.NR1-H5252-1mg
Price: 2200 USD
Availability: InStock

Product Code

AMS.NR1-H5252-1mg

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$2,200.00

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Overview

Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.

Product Specifications

More Information
SKU	AMS.NR1-H5252-1mg
Size	1 mg
Species	Human
Expression Host	HEK293
Gene symbol	Neuropilin-1
aa sequence	Phe 22 - Lys 644
Tag	FC
Label/Conjugate	Unconjugated
Accession No	AAH07533
Gene synonyms	NRP1,Neuropilin-1,NRP,VEGF165R,CD304
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Immobilized Human VEGF165, Tag Free (Cat. No. VE5-H4210) at 2 ?g/mL (100 ?L/well) can bind Human NRP1, Fc Tag (Cat. No. NR1-H5252) with a linear range of 0.2-3 ng/mL (QC tested).

Human NRP1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

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Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag

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