Human IL-18BP Protein, Fc Tag (MALS verified)

Name: Human IL-18BP Protein, Fc Tag (MALS verified)
Brand: AMS.ILP-H5253-200ug
SKU: AMS.ILP-H5253-200ug
Price: 365 USD
Availability: InStock

Product Code

AMS.ILP-H5253-200ug

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$365.00

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Overview

Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.

Product Specifications

More Information
SKU	AMS.ILP-H5253-200ug
Size	200 ug
Species	Human
Expression Host	HEK293
Gene symbol	IL-18BP
aa sequence	Thr 31 - Gly 194
Tag	FC
Label/Conjugate	Unconjugated
Accession No	NP_001138529
Gene synonyms	IL18BP,IL18BPa,Tadekinig-alfa
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

Images

Human IL-18BP, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

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Human IL-18BP Protein, Fc Tag (MALS verified)

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