Mouse CD3 epsilon Protein, Fc Tag
Product Code
AMS.CDE-M5256-1mg
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CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
| SKU | AMS.CDE-M5256-1mg |
|---|---|
| Size | 1 mg |
| Species | Mouse |
| Expression Host | HEK293 |
| Gene symbol | CD3 epsilon |
| aa sequence | Asp 23 - Asp 108 |
| Tag | FC |
| Label/Conjugate | Unconjugated |
| Accession No | N/A |
| Gene description | Mouse |
| Gene synonyms | FLJ18683,T3E,TCRE,CD3E,CD3-epsilon |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | RT |
| Supplier Name | ACROBiosystems Inc. |
