Cynomolgus CD3 epsilon Protein, Fc,His Tag

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AMS.CDE-C5254-100ug
$440.00
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CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
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SKU AMS.CDE-C5254-100ug
Size 100 ug
Species Monkey, Cynomolgus
Expression Host HEK293
Gene symbol CD3 epsilon
aa sequence Gln 22 - Asp 117
Tag His, FC
Label/Conjugate Unconjugated
Accession No N/A
Gene description Cynomolgus
Gene synonyms FLJ18683,T3E,TCRE,CD3E,CD3-epsilon
Format Powder
Storage -20C
Shipping Temp RT
Supplier Name ACROBiosystems Inc.