TrkA Assay Kit

Product Code
AMS.79548
$0.00
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The tropomyosin receptor kinases (TRK) are a family of tyrosine receptor kinases|which include TrkA|TrkB and TrkC. TrkA is activated by binding to nerve growth factor (NGF)|resulting in activation of cell proliferation through the RAS/MAPK/ERK and PLCgamma/PI3K pathways. Constitutive activation of TrkA is associated with colorectal cancer|suggesting TrkA inhibitors may have potential therapeutic value. The TrkA Assay Kit is designed to measure TrkA activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The TrkA Assay Kit comes in a convenient 96-well format|with enough purified recombinant TrkA enzyme|TrkA substrate|ATP and kinase assay buffer for 100 enzyme reactions.
More Information
SKU AMS.79548
Size 96 reactions
Application Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Storage Up to 6 months when stored as recommended
Shipping Temp -80C (dry ice)
Supplier Name BPS
For more details visit our Kinases page >