TrkA Assay Kit
Product Code
AMS.79548
$0.00
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The tropomyosin receptor kinases (TRK) are a family of tyrosine receptor kinases|which include TrkA|TrkB and TrkC. TrkA is activated by binding to nerve growth factor (NGF)|resulting in activation of cell proliferation through the RAS/MAPK/ERK and PLCgamma/PI3K pathways. Constitutive activation of TrkA is associated with colorectal cancer|suggesting TrkA inhibitors may have potential therapeutic value. The TrkA Assay Kit is designed to measure TrkA activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The TrkA Assay Kit comes in a convenient 96-well format|with enough purified recombinant TrkA enzyme|TrkA substrate|ATP and kinase assay buffer for 100 enzyme reactions.
SKU | AMS.79548 |
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Size | 96 reactions |
Application | Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
Storage | Up to 6 months when stored as recommended |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |