TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody

Product Code
Order Support
Shipping Information
Product Updates
  • Keep up to date with product offers, resources and news

  • Sign up

Catalytic activity:ATP-dependent breakage|passage and rejoining of double-stranded DNA.|enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.|Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils|whereas prokaryotic enzymes relax only negative supercoils.|PTM:Phosphorylation has no effect on Catalytic activity.|Belongs to the type II topoisomerase family.|subcellular location:Generally located in the nucleoplasm.|subunit:Homodimer. Interacts with COPS5.|
More Information
SKU AMS.BT-AP13123-100ul
Size 100 ul
Host species Rabbit
isotype IgG
Application WB, ELISA
Species reactivity Human, Mouse, Rat
Gene synonyms TOP2A ;Phospho Ser1213; DNA topoisomerase 2-alpha; EC; DNA topoisomerase II; alpha isozyme
Storage -20C for 1 year