Spike S1 (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit
Product Code
AMS.79954
$0.00
Order Support
-
Email: [email protected]
Order Support
- Email: [email protected]
Order Support
- Email: [email protected]
Order Support
-
T: +1 (800) 987 0985 (toll free)
-
Email: [email protected]
Order Support
-
Email: [email protected]
Shipping Information
-
Delivery charges will be calculated during checkout
Product Updates
-
Keep up to date with product offers, resources and news
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As a first step of the viral replication strategy|the virus attaches to the host cell surface before entering the cell. The Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes|endothelial cells|and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer some protection against the viral infectionThe SARS-CoV-2 Spike S1:ACE2 Inhibitor Screening Colorimetric Assay Kit is designed for screening and profiling inhibitors of this interaction. The key to this kit is the high sensitivity of detection of ACE2-Biotin protein by Streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First|Spike S1 protein is attached to a 96-well transparent plate. Next|ACE2-Biotin is incubated with Spike S1 on the plate. Finally|the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce color|which can then be measured using a UV/Vis spectrophotometer microplate reader.
SKU | AMS.79954 |
---|---|
Size | 96 reactions |
Application | This kit is useful for screening for inhibitors of ACE2 binding to SARS-CoV-2 Spike. |
Species reactivity | SARS-CoV-2 |
Gene synonyms | coronavirus, SARS-CoV-2 inhibition kit, ACE2 inhibition kit, SARS TR-FRET kit, ACE2 homogenous kit, covid, covid-19, covid19, Sars-cov-2, sars cov 2, sarscov2 |
Storage | Up to 6 months from date of receipt# when stored as recommended. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |