Spike (B.1.351/ Beta Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luc Reporter)
Product Code
AMS.78142-2
$0.00
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The Spike (SARS-CoV-2) (B.1.351) Pseudotyped Lentivirus were produced with SARS-CoV-2 B.1.351 Variant Spike (Genbank Accession #QHD43416.1 with B.1.351 mutations (L18F/ D80A/ D215G/ R246I/ K417N/ E484K/ N501Y/ D614G/ A701V) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter/ therefore/ the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2) (B.1.351) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 B.1.351 variant in a Biosafety Level 2 facility.
SKU | AMS.78142-2 |
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Size | 500 ul x 2 |
Species | SARS-CoV-2 |
Application | 1. Study the mechanism of viral transduction of SARS-CoV-2 B.1.351 variant. 2. Screening for neutralizing antibodies inhibiting the binding of SARS-CoV-2 Spike (B.1.351 variant) to ACE2. |
Gene synonyms | Sars-cov-2 B.1.351, 20H/501Y.V2, sars cov 2, sarscov2, South Africa variant, S. Africa lenti, South African mutation, B1351 lentivirus, pseudovirus, pseudovirion, 78142-1, 78142-2 |
Storage | Lentiviruses are shipped with dry ice. For long term storage/ it is recommended to store the virus at -80C. Avoid repeated freeze-thaw cycles. Titers can drop significantly with each freeze-thaw cycle. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |