SNX13 Rabbit Polyclonal Antibody

Product Code
AMS.BT-AP12702-100ul
$230.00
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This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain|and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s)|accelerates its GTP hydrolysis|and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role|this protein may link heterotrimeric G protein signaling and vesicular trafficking.
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SKU AMS.BT-AP12702-100ul
Size 100 ul
Host species Rabbit
isotype IgG
Application WB
Species reactivity Human, Mouse
Gene synonyms SNX13; Sorting nexin-13; RGS domain- and PHOX domain-containing protein; RGS-PX1
Storage -20C for 1 year