Sirtuin 6 Fluorogenic Assay Kit

Product Code
AMS.50022
$0.00
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The Sirtuin 6 Fluorogenic Assay Kit is a complete assay system designed to measure SIRT6 activity for screening and profiling applications. It comes in a convenient 96-well format|with all the reagents necessary for 100 fluorescent SIRT6 activity measurements. In addition|the kit includes purified SIRT6 enzyme and a SIRT inhibitor|Nicotinamide|for use as a positive and negative control|respectively. The Fluorogenic SIRT6 Assay Kit is based on a unique fluorogenic substrate and developer combination. This assay method eliminates dealing with the radioactivity|extraction|and chromatography aspects of traditional assays. Using this kit|only two simple steps on a microtiter plate are needed to analyze the SIRT6 activity level. First|the Sirtuin 6 fluorometric substrate|containing a myristoylated lysine side chain|is incubated with purified SIRT6 enzyme. The demyristoylation sensitizes the substrate so subsequent treatment with the SIRT Developer produces a fluorophore that can then be measured using a fluorescence reader.
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SKU AMS.50022
Size 96 reactions
Application Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Gene synonyms SIRT6, Sirtuin 6, SIRT, SIRT 6, Fluorogenic Sirtuin 6 Assay Kit
Storage Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Shipping Temp -80C (dry ice)
Supplier Name BPS
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