Sirtuin 6 Fluorogenic Assay Kit
Product Code
AMS.50022
$0.00
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The Sirtuin 6 Fluorogenic Assay Kit is a complete assay system designed to measure SIRT6 activity for screening and profiling applications. It comes in a convenient 96-well format|with all the reagents necessary for 100 fluorescent SIRT6 activity measurements. In addition|the kit includes purified SIRT6 enzyme and a SIRT inhibitor|Nicotinamide|for use as a positive and negative control|respectively. The Fluorogenic SIRT6 Assay Kit is based on a unique fluorogenic substrate and developer combination. This assay method eliminates dealing with the radioactivity|extraction|and chromatography aspects of traditional assays. Using this kit|only two simple steps on a microtiter plate are needed to analyze the SIRT6 activity level. First|the Sirtuin 6 fluorometric substrate|containing a myristoylated lysine side chain|is incubated with purified SIRT6 enzyme. The demyristoylation sensitizes the substrate so subsequent treatment with the SIRT Developer produces a fluorophore that can then be measured using a fluorescence reader.
SKU | AMS.50022 |
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Size | 96 reactions |
Application | Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
Gene synonyms | SIRT6, Sirtuin 6, SIRT, SIRT 6, Fluorogenic Sirtuin 6 Assay Kit |
Storage | Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |