SHP-1(Phospho-Tyr564) Rabbit Polyclonal Antibody

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth|differentiation|mitotic cycle|and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains|which act as protein phospho-tyrosine binding domains|and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells|and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with|and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene|which encode distinct isoforms|have been reported.
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SKU AMS.BT-AP12654-100ul
Size 100 ul
Host species Rabbit
isotype IgG
Application WB
Species reactivity Human, Mouse
Gene synonyms SHP-1 ;Tyr564 ; Tyrosine-protein phosphatase non-receptor type 6; EC; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
Storage -20C for 1 year