SBE Reporter Kit (TGF?/SMAD signaling pathway)

Product Code
AMS.60654
$0.00
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The SBE Reporter kit is designed for monitoring the activity of TGF?/SMAD signaling pathway in the cultured cells. The kit contains transfection-ready SBE luciferase reporter vector|which is a TGF? pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized SBE responsive element located upstream of a minimal promoter. The SBE reporter is premixed with constitutively-expressing Renilla luciferase vector that serves as internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as negative control. The noninducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter|without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity.
More Information
SKU AMS.60654
Size 500 reactions
Application • Monitor TGF? signaling pathway activity.
• Screen for activators or inhibitors of the TGF?/ SMAD signaling pathway.
• Study effects of RNAi or gene overexpression on the activity of the TGF? pathway.
Gene synonyms SBE reporter, TGFbeta reporter, TGFbeta reporter, SMAD reporter
Format assay kit
Storage Stable at least 12 months from date of receipt# when stored as directed (-20C)
Shipping Temp -20C
Supplier Name BPS
Research Areas Immunology
For more details visit our Immunotherapy page >