SARS-CoV-2 Spike Trimer (P26S, HV69-70del, V126A, Y144del, LLA241-243del, H245Y, S477N, E484K, D614G, P681H, T1027I, D1118H), His Tag (MALS verified)
Product Code
AMS.SPN-C52Hh-50ug
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SARS-CoV-2 Spike Trimer, His Tag (SPN-C52Hh) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations (P26S, HV69-70del, V126A, Y144del, LLA241-243del, H245Y, S477N, E484K, D614G, P681H, T1027I, D1118H) were identified in the SARS-CoV-2 variant B.1.620, which was found to circulate in Europe and Central Africa. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
SKU | AMS.SPN-C52Hh-50ug |
---|---|
Size | 50 ug |
Species | Virus, SARS-CoV-2 |
Expression Host | HEK293 |
Gene symbol | Spike protein |
Tag | His |
Accession No | QHD43416.1 |
Gene synonyms | Spike,S protein,Spike glycoprotein,S glycoprotein |
Format | Powder |
Storage | -20C |
Shipping Temp | RT |
Supplier Name | ACROBiosystems Inc. |