SARS-CoV-2 (COVID-19) NSP1 Protein, His Tag

Name: SARS-CoV-2 (COVID-19) NSP1 Protein, His Tag
Brand: AMS.NS1-C51H7-100ug
SKU: AMS.NS1-C51H7-100ug
Price: 500 USD
Availability: InStock

Product Code

AMS.NS1-C51H7-100ug

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$500.00

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Overview

The viral nonstructural protein 1 (nsP1) is the only membrane-associated protein that anchors the replication complex to the cellular membranes. NSP1 inhibits host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation. By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.

Product Specifications

More Information
SKU	AMS.NS1-C51H7-100ug
Size	100 ug
Species	Virus, SARS-CoV-2
Expression Host	E. coli
Gene symbol	NSP1
Tag	His
Accession No	YP_009725297.1
Gene synonyms	NSP1,nsp1,Leader protein,Host translation inhibitor nsp1
Format	Powder
Storage	-20C
Shipping Temp	RT
Supplier Name	ACROBiosystems Inc.

For more details visit our SARS-CoV-2 and COVID-19 Recombinant Proteins and Antibodies page >

Images

SARS-CoV-2 NSP1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

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SARS-CoV-2 (COVID-19) NSP1 Protein, His Tag

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