
RNAdvantage
Room Temperature RNA Stabilization in Tissue
Protects your RNA from degradation with no need to keep it frozen
RNAdvantage is a non-toxic RNA stabilization solution that allows for relaxed sample handling and analysis.
• Protects and stabilizes RNA for 14 days
• Subsequent RNA suitable for RNAseq
• No rush for immediate downstream processing
Features
With no need for immediate flash freezing, you can be flexible with your use and storage of RNA samples
• Rapid RNase inactivation
• No rtPCR inhibition
• High RNA integrity for RNAseq
• Store and transport at RT after collection
Applications
RNAdvantage can be used for RNA preservation with most tissues, cultured cells, bacteria, and yeast.
RNAdvantage Solution has been tested with animal tissues, including brain, heart, kidney, spleen, liver and lung. It is also effective for RNA preservation in white blood cells, PMBCs and some plant tissues.
Simple, integrated workflow

Reliable samples for RNAseq
RIN values when using RNAdvantage meet or exceed the required levels for core sequencing facilities, even when tissue samples are stored for 14 days at room temperature. This ensures excellent sequencing results due to the robust stabilization provided by RNAdvantage. All of this, while reducing shipping and storage costs.

RNAdvantage fits into AMSBIO's suite of RNA protection products:
- RNAdvantage - protects RNA in tissue samples at room temperature
- RNAssure - protects RNA during the eluting phase of purification
- RNArchive - protects RNA for safe shipping and storage at room temperature

Flexible storage for varied requirements
Storage Condition | Length of protection |
---|---|
Room temperature (15-25°C) | 7-14 days |
Refrigeration (2-4°C) | 2 months |
Frozen (-80°C) | >1 Year |
RNAdvantage Frequently Asked Questions
- The composition of RNAdvantage is proprietary but can be considered similar to that of Thermo Fisher's RNAlater
- Yes, the tissue is simply removed from the solution,
blotted to remove any excess solution and can be used
directly following the instructions for the RNA purification
protocol.
- A The density of the RNAdvantage solution may be higher
than the tissue sample causing it to float. Gently invert the
tube till the RNAdvantage can permeate the tissue sample
sufficiently to allow the sample to sink into the solution.