RET Assay Kit

Product Code
AMS.79566
$0.00
Order Support
Shipping Information
Product Updates
  • Keep up to date with product offers, resources and news

  • Sign up

RET is a receptor kinase for GDNF (glial cell-line derived neurotrophic factor) family ligands (GFLs). Activation of wild-type RET is important in several cancers where it contributes to tumor progression through various mechanisms. In addition|it has been shown that activating mutation as well as RET rearrangement that leads constitutively active protein plays a significant role in various cancer types. Importantly|small molecule inhibitors of RET have been clinically proved as a promising therapeutic reagent in medullary thyroid cancer and are being evaluated for other types of cancers related to RET overexpression or mutation. The RET Assay Kit is designed to measure RET activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The RET Assay Kit comes in a convenient 96-well format|with enough purified recombinant RET enzyme|RET substrate peptide (IRF-1Rtide)|ATP and kinase assay buffer for 100 enzyme reactions.
More Information
SKU AMS.79566
Size 96 reactions
Application Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Storage Up to 6 months when stored as recommended.
Shipping Temp -80C (dry ice)
Supplier Name BPS
For more details visit our Kinases page >