Recombinant Nucleosome (E. coli-derived)

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AMS.52038
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Human recombinant nucleosomesconsisting of 147 bp DNA (PCR) and 2 moleculeseach of histones H2A (a.a. 2-130(end))|H2B(a.a. 2-126(end))|H3 (a.a. 2-137(end))|and H4(a.a. 2-103(end))|expressed in an E. coliexpression system. GenBank Accession Nos. areNM_033445|NM_003528|NM_003532|andNM_003548|respectively. Each histone proteinhas an N-terminal His-tag. Total histone MW =113.8 kDa.
More Information
SKU AMS.52038
Size 100 ug
Species Human
Expression Host E. coli
aa sequence H2A 2-130(end), H2B 2-126(end), H3 2-137(end), H4 2-103(end)
Application Substrate for histone methyltransferase assays. Ideal for screening small molecular inhibitors of histone methyltransferases for drug discovery and HTS applications.
Accession No NM_033445, NM_003528, NM_003532, and NM_003548
Gene id NM_033445, NM_003528, NM_003532, and NM_003548
Format Aqueous buffer solution
Storage At least 6 months at -80C.
Shipping Temp -80C (dry ice)
Supplier Name BPS
Research Areas Epigenetics
For more details visit our Histone Methylation page >