PPR1A Polyclonal Antibody

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Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,
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SKU AMS.BT-AP13271-100ul
Size 100 ul
Host species Rabbit
isotype IgG
Application WB, ELISA
Species reactivity Human, Mouse, Rat
Gene synonyms Protein phosphatase 1 regulatory subunit 1A ;Protein phosphatase inhibitor 1;I-1;IPP-1
Storage -20C for 1 year