PD-1:PD-L2[Biotinylated] Inhibitor Screening Colorimetric Assay Kit
Product Code
AMS.72017
$0.00
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Cell signaling through the PD-1 receptor upon binding the PD-L2 ligandattenuates immune responses and is exploited by both tumors and viruses. The PD-1:PDL2[Biotinylated] Inhibitor Screening Colorimetric Assay Kit is designed for screening inhibitors ofPD-L2 ligand binding to PD-1 receptor. The key to this kit is the high affinity of biotin-labeled PD-L2 for streptavidin-HRP.Only a few simple steps on a microtiter plate are required for the assay. First|PD-1 is coated ona 96-well plate. Next|PD-L2 is incubated with PD-1 on the plate. Finally|the plate is treated withstreptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color|whichcan then be measured using a UV/Vis spectrophotometer microplate reader.
SKU | AMS.72017 |
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Size | 96 reactions |
Application | This kit is most useful for screening for inhibitors of PD1 binding to PD-L2. |
Gene synonyms | Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L and Programmed Cell Death 2 Ligand 2, PDL2, PD-L2, CD273, PDCDL1G2, B7-DC |
Storage | Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |
Research Areas | Immunology |