PD-1[Biotinylated]:PD-L2 Inhibitor Screening Colorimetric Assay Kit

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AMS.72019
$0.00
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Cell signaling through the PD-1 receptor upon binding the PD-L2 ligandattenuates immune responses and is exploited by both tumors and viruses. The PD-1[Biotinylated]:PD-L2 Inhibitor Screening Colorimetric Assay Kit is designed for screeninginhibitors of PD-1 receptor binding to PD-L2 ligand. The key to this kit is the high affinity of biotin-labeled PD-1 forstreptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First|PD-L2 is coated on a 96-well plate. Next|PD-1 is incubated with PD-L2 on the plate. Finally|theplate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substratesubstrate to produce color|which can then be measured using a UV/Vis spectrophotometermicroplate reader.
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SKU AMS.72019
Size 96 reactions
Application This kit is most useful for screening for inhibitors of PD-L2.
Gene synonyms Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L and Programmed Cell Death 2 Ligand 2, PDL2, PD-L2, CD273, PDCDL1G2, B7-DC
Storage Stable at least 6 months from date of receipt# when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Shipping Temp -80C (dry ice)
Supplier Name BPS
Research Areas Immunology
For more details visit our Immunotherapy page >