Our body produces molecules in cells called Antioxidants. These act as the body’s defense to keep free radicals in check and help protect the body from oxidative stress. Antioxidants can donate an electron to a free radical without making themselves unstable. This causes free radicals to stabilise and become less reactive, preventing damage to cells.
Antioxidant preservatives also play a crucial role in food production by increasing shelf life. Examples of antioxidants include vitamins A, C, and E.
Oxidative stress occurs when there is an imbalance of free radicals and antioxidants (too many free radicals and too few antioxidants).
The effect of Oxidative Stress on the body
When there are more free radicals present than can be kept in balance by antioxidants, the free radicals can start doing damage to fatty tissue, DNA and proteins in your body. This damage can lead to a vast number of diseases over time which include:
- Inflammatory conditions
- Heart disease
- Neurodegenerative diseases, such as Alzheimer's and Parkinson's
- Also contributes to aging (which has been defined as a gradual accumulation of free-radical damage, according to Christopher Wanjek, the Bad Medicine columnist for Live Science)
AMSBIO is offering an extensive range of antibodies and assays for oxidative modification, redox modulators and inflammatory biomarkers as follows: