Neural Stem Cells, Neurons & Astrocytes

AMSBIO offers a range of neural stem cells (NSCs) and neural lineage progenitors (astrocytes, cortical neurons and dopaminergic neurons), derived from control human iPSCs using non-integrating episomal-based differentiation methods. We also provide optimized media and kits for easy differentiation to high quality neural lineage cells.

Benefits

  • High purity neurons: >90% Tuj1+ neurons and < 5% GFAP+ cells
  • High cell viability of neurons post-thaw (>80%)
  • Isogenic lineages of mixed neurons and associated neuronal derivatives available from two different control iPSC lines (male ASE-9109 and female ASE-9110)
  • Functionally viable neurons capable of neuronal excitability and synapse formation
  • Long-term viability in cell culture and consistency in results (>30 days): affords greater flexibility in designing high throughput drug screening and testing

Applications

  • Electrophysiology and synaptic functionality assays
  • Neurotoxicity and neuroprotection screening tests
  • Physiologically relevant disease modelling platform
  • Gene profiling under isogenic conditions to understand gene functionality associated with neurological diseases

NameDatasheetPacksize Order
Astro Induction Media100 ml View
Astro Maturation Media100 ml View
Astrocytes Mature (iPSC from Blood Cells; Female)-1 vial (1 x 10^6) View
Astrocytes Mature (iPSC from Blood Cells; Male)1 vial (1 x 10^6) View
Astrocytes Precursors (iPSC from Blood Cells; Female)1 vial (1 x 10^6) View
Astrocytes Precursors (iPSC from Blood Cells; Male)-1 vial (1 x 10^6) View
Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Female)1 kit View
Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Male)-1 kit View

Benefits

  • High purity (>90%) cells expressing neural stem cell markers: SOX1, PAX6 and Nestin
  • Fully characterized by immunocytochemistry and whole genome profiling
  • Provides a consistent and reliable source of differentiated mature, functional neurons and glial cells

Applications

  • Neurotoxicity screening
  • Neuroprotection assays and research
  • Drug screening
  • Reliable predictable models of neurological disorders

NameDatasheetPacksize Order
DOPA Induction Media-100 ml View
DOPA Maturation Media-100 ml View
Dopaminergic Neurons (iPSC from Blood Cells; Female)1 vial View
Dopaminergic Neurons (iPSC from Blood Cells; Male)1 vial View
Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Female)-1 vial View
Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Male)1 vial View