LRP6 Polyclonal Antibody
Product Code
AMS.BT-AP10976-100ul
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This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
SKU | AMS.BT-AP10976-100ul |
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Size | 100 ul |
Host species | Rabbit |
isotype | IgG |
Application | WB, ELISA |
Species reactivity | Human, Mouse |
Gene synonyms | Low-density lipoprotein receptor-related protein 6 ;LRP-6 |
Storage | -20C for 1 year |