LDN193189 HCl
Product Code
AMS.MC-4764
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LDN-193189 HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripotent stem cells.2-3 LDN-193189 HCl has also been used to examine the role of osteogenesis in prostate tumor metastases in bone.4
SKU | AMS.MC-4764 |
---|---|
Size | 25 mg |
Cas no | 1062368-62-0 |
Storage | -20°C |
Shipping Temp | Ambient |
Supplier Name | Med Chem 101 LLC |