SPTN2 Rabbit Polyclonal Antibody
Product Code
AMS.BT-AP04875-50ul
Order Support
-
Email: [email protected]
Order Support
- Email: [email protected]
Order Support
- Email: [email protected]
Order Support
-
T: +1 (800) 987 0985 (toll free)
-
Email: [email protected]
Order Support
-
Email: [email protected]
Shipping Information
-
Delivery charges will be calculated during checkout
Product Updates
-
Keep up to date with product offers, resources and news
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2)|is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to|but distinct from|the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia|SCA5|that is characterized by neurodegeneration|progressive locomotor incoordination|dysarthria|and uncoordinated eye movements.
SKU | AMS.BT-AP04875-50ul |
---|---|
Size | 50 ul |
Host species | Rabbit |
isotype | IgG |
Application | WB |
Species reactivity | Human, Rat |
Gene synonyms | SPTN2 |
Storage | -20C for 1 year |
Shipping Temp | Gel Packs |