SPTN2 Rabbit Polyclonal Antibody

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AMS.BT-AP04875-50ul
$150.00
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Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2)|is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to|but distinct from|the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia|SCA5|that is characterized by neurodegeneration|progressive locomotor incoordination|dysarthria|and uncoordinated eye movements.
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SKU AMS.BT-AP04875-50ul
Size 50 ul
Host species Rabbit
isotype IgG
Application WB
Species reactivity Human, Rat
Gene synonyms SPTN2
Storage -20C for 1 year
Shipping Temp Gel Packs