SPTA1 Rabbit Polyclonal Antibody

Product Code
AMS.BT-AP04870-50ul
$150.00
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Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton|and functions in the determination of cell shape|arrangement of transmembrane proteins|and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin|which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders|including elliptocytosis type 2|pyropoikilocytosis|and spherocytic hemolytic anemia.
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SKU AMS.BT-AP04870-50ul
Size 50 ul
Host species Rabbit
isotype IgG
Application WB
Species reactivity Human, Mouse
Gene synonyms SPTA1
Storage -20C for 1 year
Shipping Temp Gel Packs