Kpm Polyclonal Antibody

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LATS2 encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
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SKU AMS.BT-AP04866-50ul
Size 50 ul
Host species Rabbit
isotype IgG
Application IF, IHC-P, ELISA
Species reactivity Human, Mouse
Gene id 26524
Gene synonyms LATS2; KPM; Serine/threonine-protein kinase LATS2; Kinase phosphorylated during mitosis protein; Large tumor suppressor homolog 2; Serine/threonine-protein kinase kpm; Warts-like kinase
Storage -20C for one year
Shipping Temp Gel Packs