KLHL3 Polyclonal Antibody

Product Code
AMS.BT-AP04845-50ul
$150.00
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KLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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SKU AMS.BT-AP04845-50ul
Size 50 ul
Host species Rabbit
isotype IgG
Application WB, IF, IHC-P, ELISA
Species reactivity Human
Gene synonyms KLHL3; KIAA1129; Kelch-like protein 3
Storage -20C for one year
Shipping Temp Gel Packs