KIM-1 Tests for Kidney Damage Detection
Lateral Flow and ELISA tests
We offer the first rapid test for early detection of kidney damage, which is caused by therapeutic agents & drug induction. Avoid traditionally insensitive renal disease testing and switch to rapid and specific tests for the early detection on kidney damage. The Kidney Injury Molecule-1 (KIM-1) is a novel biomarker for renal diseases (designated as Kim-1 in rodents, KIM-1 in humans). The kidney injury molecule-1 is a type 1 transmembrane protein, with an immunoglobulin and mucin domain, whose expression is markedly up-regulated in the proximal tubule in the post-ischemic rat kidney but undetectable in normal kidneys. The KIM-1 ectodomain is cleaved, allowing it to be detectable in urine, and making it a great marker for renal damage.
AMSBIO provides both ELISA and lateral-flow strip tests for both rat and human KIM-1, and also offers a hand held reader to quantify lateral-flow assays. These products can be combined to achieve an effective solution for kidney damage testing.
H-Rena-strip™ and R-Rena-strip™ lateral-flow tests
- Fast test results in just 15 minutes
- Reliable: specificity 96% and sensitivity 99%
- Easy to use no special training necessary
- Semi-quantitative results can be correlated with color chart
- Quantitative results with hand-held reader
The Rena-strip is a highly sensitive lateral-flow assay for the detection of KIM-1 (human) and Kim-1 (rat) novel biomarkers in samples from human and rat urine respectively. Many government organizations and agencies (FDA, EMA etc.) recognize KIM-1 as an excellent tool in pre-clinical study to monitor acute kidney tubular toxicity and has been shown to be the highest performing of all conventional kidney damage markers.
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Bulk sizes and pricing are available for all of the kidney-damage assay kits.
Hand-held assay readers for lateral-flow assays
An easy to use, battery operated assay reader for quantifiable lateral-flow assays. Barcode reader is integrated. The device may be custom programmed for rapid assay quantification. USB connectivity to other devices, including an optional printer.
ELISA tests
AMSBIO also offers a selection of ELISA and CLIA (Chemiluminescent Immunoassays) kits for detection and quantification of Kidney Injury Molecule-1 in human, mouse and rat samples, as well as other model species. Browse links below to find out more.
Search all Kidney Injury Molecule-1 ELISA kits
H-Rena-strip™ and R-Rena-strip™ are trademarks of Bioassay Works.