JNK1/2/3(Phospho Thr183/Y185) Polyclonal Antibody
Product Code
AMS.BT-AP10581-100ul
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl
| SKU | AMS.BT-AP10581-100ul |
|---|---|
| Size | 100 ul |
| Host species | Rabbit |
| isotype | IgG |
| Application | WB, IF, IHC-P, ICC, ELISA |
| Species reactivity | Human, Mouse, Rat, Chicken |
| Gene synonyms | Mitogen-activated protein kinase 8/9/10; MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi |
| Storage | -20C for 1 year |
